Toolkits for DNA vaccine design, an update
The symposium was hosted by Mechninov ́s Institute of Vaccine and Sera, November 17‐21, 2016, Moscow. Here is the full program for the event:
| Start | Finish | Title | Presenter | |
|---|---|---|---|---|
| For questions or suggestions, please contact the organizers. | ||||
| 9:00 | 10:00 | Registration | Mechninov ́s Institute of Vaccine and Sera, Mali Kazenny pereulok 5a, building 9 | |
| 10:00 | 10:15 | Opening | Welcome by Prof, Academician Zverev Vitaly V, the Director of the Mechnikov ́s Institute of Vaccine and Sera | |
| 10:15 | 11:00 | Can a DNA cancer vaccine turn out to be an anti‐inflammatory gene therapy? | Shneider Alexander (CureLab Oncology, Inc., Boston, USA; University of Ariel, Ariel, Israel; OOO CL Oncology, Moscow, Russia) | |
| 11:00 | 11:30 | COFFEE‐BREAK Mali Kazenny pereulok 5a, building 16 & POSTER VIEWING | ||
| 11:30 | 12:00 | Protein against DNA, a review of vaccines against hepatitis B virus | Sominskaya Irina (Biomedical Research and Study Center, Riga, Latvia) | |
| 12:00 | 12:30 | Pre‐clinical development of recombinant BCG based HIV vaccine. Lessons learned | Joan Joseph (Fundacio Clinic, Barcelona, Spain) | |
| 12:30 | 12:50 | Progress in Zika virus vaccine development | Žusinaite Eva (Institute of Technology, Tartu University, Tartu, Estonia) | |
| 13:00 | 14:00 | >LUNCH Mali Kazenny pereulok 5a, building 16 | ||
| 14:00 | 14:30 | Viral RNA nucleotide content is affected by innate immune system recognition – implications for vector design | Lukashev Alexander (MP Chumakovs ́s Federal Research Center for Study and Development of Immunobiological Preparations, Moscow, Russia) | |
| 14:30 | 15:00 | HIV enzymes as prototype immunotherapeuticals against drug resistance: preclinical trials in mice | Isaguliants Maria (Riga Stradins University, Riga, Latvia; Karolinska Institutet. Stockholm, Sweden; MP Chumakovs ́s Federal Research Center for Study and Development of Immunobiological Preparations, and Gamaleya Research Center of Epidemiology and Microbiology, Moscow, Russia) | |
| 15:00 | 15:20 | Multicomponent DNA vaccine based on HIV‐1 clade A enzymes induces cellular response of diverse profile in mice | Latanova Anastasia (WA Englehardt Institute of Molecular Biology, Moscow, Russia; Karolinska Institutet, Stockholm, Sweden) | |
| 15:30 | 16:00 | COFFEE‐BREAK Mali Kazenny pereulok 5a, building 16 & POSTER VIEWING | ||
| 16:00 | 16:30 | Optimization of design and delivery of HIV reverse transcriptase based prototype DNA vaccines in a mouse model | Starodubova Elizaveta (WA Englehardt Institute of Molecular Biology, Moscow, Russia; Karolinska Institutet, Stockholm, Sweden) | |
| 16:30 | 16:45 | Single immunization with codon‐optimized gene of consensus rabies virus glycoprotein is able to elicit neutralizing antibodies in mice | Pankova Ekaterina (WA Englehardt Institute of Molecular Biology, Moscow, Russia) | |
| 16:45 | 16:52 | Comparison of immunogenicity of HCV core and its alternative reading frame protein in mice (poster presentation) | Dovbenko Anastasija (Biomedical Research and Study Center, Riga, Latvia) | |
| 16:53 | 17:00 | Comparative immunogenicity of HIV‐1 reverse transcriptase of clades A and B in mice (poster presentation) | Starodubova Elizaveta (WA Englehardt Institute of Molecular Biology, Moscow, Russia; Karolinska Institutet. Stockholm, Sweden) | |
| 07:45 | Transportation by buss of conference participants to the Chumakov ́s Institute of poliomyelitis, Moscovsky Settlement | OBS! Only for registered conference participants. Preference to participants staying at hotel Agios | ||
| 08:45 | 09:15 | Registration at the MP Chumakovs ́s Federal Research Center for Study and Development of Immunobiological Preparations, Moskovsky Settlement, Moscow | OBS!!! Passports are requested for presentation by all participants. Now access to the conference venue without a pass! | |
| 09:15 | 09:30 | Welcome by Prof, Academician Ishmukhametov Aidar A, the Director of the MP Chumakovs ́s Federal Research Center for Study and Development of Immunobiological Preparations | ||
| 09:30 | 10:15 | Adjuvants for DNA vaccines: from ad hock vaccine design to technology platforms | Shneider Alexander (CureLab Oncology, Inc., Boston, USA; University of Ariel, Ariel, Israel; OOO CL Oncology, Moscow, Russia) | |
| 10:15 | 10:45 | Adjuvants and their application: Update and the flagellin case | Rhee Joon Haeng (Chonnam National University Medical School, Gwangju, Republic of Korea) | |
| 10:45 | 11:15 | Dendrimer complexes as a platform for gene delivery | Dzmitruk Volha (Institute of Biophysics and Cell Engineering of NASB, Minsk, Belarus) | |
| 11:15 | 11:30 | Visualization and quantification of protein expression after gene electroporation in vivo | Gordeychuk Ilya (MP Chumakovs ́s Federal Research Center for Study and Development of Immunobiological Preparations; Karolinska Institutet, Stockholm, Sweden) | |
| 11:30 | 12:00 | COFFEE BREAK | ||
| 12:00 | 12:45 | The Results of Phase II Clinical Trial of HIV Therapeutic Optimized DNA Vaccine: The Possible Reach of Viral Reservoirs | Kozlov Andrei (The Biomedical Center and Peter the Great Polytechnic University, St Petersburg, Russia) | |
| 12:45 | 13:15 | Vaccines against HIV‐1 and other infectious and somatic diseases, developed in State Research Center of Virology and Biotechnology "Vector" | Karpenko Larisa (State Research Center of Virology and Biotechnology “Vector”, Koltzovo, Novosibirsk, Russia) | |
| 13:15 | 13:35 | The development of research universities as a new business model for production of innovative vaccines | Chubarev Vladimir (Institute of Pharmacy and Translational Medicine, IM Sechenov First Moscow State Medical University, Moscow, Russia) | |
| 13:35 | 13:40 | Detection and resuscitation of viable but nonculturable bacteria in vaccines and other biomedical preparations (poster presentation) | Blinkova Larisa P (Mechnikov Research Institute for Vaccine and Sera, Moscow, Russia) | |
| 13:40 | 14:40 | LUNCH | ||
| 14:40 | 15:00 | Spidroin‐based bioartificial matrix with therapeutic agents for regenerative medicine | Guryeva Svetlana (IM Sechenov First Moscow State Medical University, Moscow, Russia) | |
| 15:00 | 15:20 | Targeting at gluten intolerance culprit: development of enzymatic tools for effective gluten detoxification | Zamyatnin Jr. Andrey (IM Sechenov First Moscow State Medical University, Moscow, Russia) | |
| 15:20 | 15:40 | Ruthenium dendrimers as anticancer delivery agents | Michlewska Sylwia & Maksim Ionov (Lodz University, Lodz, Poland) | |
| 15:40 | 16:00 | Determination of parameters defining accuracy of widefield FRET measurements of molecular interactions | Kalis Martins (Riga Stradins University, Riga, Latvia) | |
| 16:00 | 16:10 | Low molecular weight compounds inhibiting the acid‐sensing ion channels (poster presentation) | Osmakov Dmitry (IM Sechenov First Moscow State Medical University, Moscow, Russia) | |
| 16:10 | 16:20 | Antioxidant premedication as a new approach to prevention of perioperative corneal abrasions (poster presentation) | Zernii Evgeni (Belozersky Institute of Physico‐Chemical Biology, Lomonosov Moscow State University) | |
| 16:20 | 16:50 | COFFEE & MINGLE | ||
| 17:00 | Transportation of conference participants by buss from Federal Research Center, Moscovsky Settlement, to hotel Agios | |||
| 18:30 | 21:30 | Conference dinner at the restaurant “Zolotya Ribka”, address: ulitza Solyanka 11/6‐1 | ||
| 10:00 | 10:40 | The packaging of chromosomes, epigenome is a regulator of nuclear processes | Östlund Farrant Anna‐Karin (Department of Molecular Biosciences, The Wenner‐Gren Institute, Stockholm University, Stockholm, Sweden) | |
| 10:40 | 11:20 | Regulation of transcription, exploiting advances in genome biology to understand and program immune response | Belikov Sergey (Department of Molecular Biosciences, The Wenner‐Gren Institute, Stockholm University, Stockholm, Sweden) | |
| 11:20 | 11:50 | COFFEE‐BREAK Mali Kazenny pereulok 5a, building 16 & POSTER VIEWING | ||
| 11:50 | 12:30 | Adjuvants: 21st century toolkit for vaccines and immunotherapeutics, with a special emphasis on mucosal routes | Rhee Joon Haeng (Chonnam National University Medical School, Gwangju, Republic of Korea) | |
| 12:30 | 12:50 | Delivery and immunogenic performance of naked DNA vaccines visualized by in vivo imaging of a novel near‐ infrared fluorescent reporter | Jansons Juris (Riga Stradins University, and Biomedical Research and Study Center, Riga, Latvia) | |
| 13:00 | 14:00 | LUNCH Mali Kazenny pereulok 5a, building 16 | ||
| 14:00 | 14:40 | DNA vaccination to activate the adaptive immune system to fight cancer | Westerberg Lisa (Department of Microbiology, Tumor and Cell Biology, Karolinska Institutet, Stockholm, Sweden) | |
| 14:40 | 15:20 | Epitope‐based vaccines and the educated search for epitopes | Reche Pedro (Complutense University of Madrid, Madrid, Spain) | |
| 15:30 | 16:00 | COFFEE‐BREAK Mali Kazenny pereulok 5a, building 16 & POSTER VIEWING | ||
| 16:00 | 16:15 | Murine breast adenocarcinoma cells expressing HIV proteins as a challenge model to test the efficacy of therapeutic HIV vaccines | Kilpeläinen Athina (Department of Microbiology, Tumor and Cell Biology, Karolinska Institutet, Stockholm, Sweden; and Fundacio Clinic, Barcelona, Spain) | |
| 16:15 | 16:30 | Immunogenicity of poliovirus non‐structural proteins during natural poliovirus infection | Prostova Maria (MP Chumakovs ́s Federal Research Center for Study and Development of Immunobiological Preparations, Moscow, Russia) | |
| 16:30 | 16:50 | Analysis of prevalence of substitutions in amino acid positions 70 and 91 of viral nucleocapsid the sustained virologic response to interferon therapy in chronic hepatitis C | Kichatova Vera (Russian Medical Academy of Postgraduate Education, and Mechnikov Research Institute for Vaccines and Sera, Moscow, Russia) | |
| 16:50 | 17:00 | Polarized macrophages use veiled surface structures to ingest HIV particles (poster presentation) | Podschwadt Philip (Ulm University, Ulm, Germany) | |
| 17:00 | 17:20 | Monitoring cell death of glioblastoma cells and immune cell interactions by IncuCyteZOOM | Sander Philip (Ulm University, Ulm, Germany) | |
| 10:00 | 10:15 | The impact of 11 low‐penetrance allelic variants on breast cancer morbidity in population of Latvia | Ustinova Monta (Riga Stradins University, Riga, Latvia) | |
| 10:15 | 10:25 | Structural pathology of the 10q23.3‐26.3 chromosome region in glioblastoma (poster presentation) | Alekseeva Ekaterina (IM Sechenov First Moscow State Medical University, Moscow, Russia) | |
| 10:25 | 10:40 | The FABP5 gene expression is significantly higher in triple‐negative sporadic than hereditary breast cancer tissues | KalninaLelde (RigaStradinsUniversity,Riga,Latvia) | |
| 10:40 | 10:55 | Expression of p53 protein in primary and secondary malignant liver tumors | Mezale Dzeina (Riga Stradins University, Riga, Latvia) | |
| 10:55 | 11:05 | Abnormal methylation MGMT, CDH1, p16/CDKNA2, DAPK, RAR‐B genes in patients with Barretts oesophagus before and after surgical treatment (poster presentation) | Osminin Sergey (IM Sechenov First Moscow State Medical University, Moscow, Russia) | |
| 11:05 | 11:15 | Analysis of telomerase activity in order to develop non‐invasive diagnosis of bladder cancer | Potoldykova Natalia (IM Sechenov First Moscow State Medical University, Moscow, Russia) | |
| 11:15 | 11:25 | Methylation of matrix and transmembrane proteins encoding genes in breast cancer | Kuznetsova Ekaterina (IM Sechenov First Moscow State Medical University, Moscow, Russia) | |
| 11:25 | 11:30 | Round table discussion on student and PhD student research activities and possibilities for collaboration | ||
| 11:30 | 12:00 | COFFEE‐BREAK Mali Kazenny pereulok 5a, building 16 & MINGLE | ||
| 10:00 | 10:30 | Differential response to malaria in two ethnic groups in Sub‐Saharan Africa | Östlund Farrant AK (Department of Molecular Biosciences, The Wenner‐Gren Institute, Stockholm University, Stockholm, Sweden) | |
| 10:30 | 11:00 | Quantification of transcription factor‐‐DNA binding affinity in a living cell | Belikov Sergey (Department of Molecular Biosciences, The Wenner‐Gren Institute, Stockholm University, Stockholm, Sweden) | |
| 11:00 | 11:30 | Flagellin as a versatile adjuvant for vaccines against intractable diseases | Rhee Joon Haeng (Chonnam National University Medical School, Gwangju, Republic of Korea) | |
| 11:30 | 11:45 | Genetic and serological diversity of hepatitis B virus in Siberia, Russia | Manuylov Victor (IM Sechenov First Moscow State Medical University, Moscow, Russia) | |
| 11:45 | 12:15 | COFFEE, MINGLE | ||
| 12:15 | 12:45 | Understanding how Wiskott‐Aldrich syndrome protein (WASp) stings in immune cells | Westerberg Lisa (Department of Microbiology, Tumor and Cell Biology, Karolinska Institutet, Stockholm, Sweden) | |
| 12:45 | 13:15 | Anti‐inflammatory gene therapy | Shneider Alex (CureLab Oncology, Inc., Boston, USA; University of Ariel, Ariel, Israel; OOO CL Oncology, Moscow, Russia) | |
| 13:15 | 13:30 | Mutation and gene expression analysis of urine sediments in non‐invasive molecular genetic diagnostics of the common oncourological diseases | Mikhaylenko Dmitry (Institute of Molecular Medicine, IM Sechenov First Moscow State Medical University, Moscow, Russia) | |
| 13:30 | 13:45 | Identification of aberrant DNA methylation in paediatric acute myeloid leukaemia by multiplex methylation sensitive PCR | Kazakova Svetlana (IM Sechenov First Moscow State Medical University, Moscow, Russia) | |
| 13:45 | 14:15 | Academic activities within Sechenov First Moscow State University | Zamyatnin Jr Andrey (IM Sechenov First Moscow State Medical University, Moscow, Russia) | |